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Evidence is increasing that every addiction without exception is related to problems with the brain's reward center, specially the mesolimbic system. This area of the problem regulates reward responses in getting food and sex, plus in nurturing infants and children. One of the most important neurotransmitters involved in reward responses, both whenever they malfunction and whenever they function properly, is dopamine. What makes opiates unique is that it, among other neurotransmitters modulates "the level of dopamine released in in reply to a stimulus"(Bostwick & Bucci, 2008). Using two separate drugs to shed weight can be very effective there are combinations while watching FDA now awaiting approval. When dealing with weight reduction and the individuals who go through it you should err along the side of caution and allow FDA do its job and demand some study be done so that the public understands the side effects and dangers of the medications before we bring them. Keep in mind that drug companies will be in business to generate money and that they would say everything to keep people on the medications. Researchers found that participants investing in this drug to get a year, lost weight within a month and have kept the weight off during the entire 56 weeks of the study. Contrave is really a combination in the drugs naltrexone and bupropion, which generally seems to reflect a new trend of weight-loss drugs which might be made up of many active ingredient, which may make them more effective and safer. Combo-pilling may be the newest fad or in addition to this the newest into the future under scrutiny and so it is just more publicly known recently, comb-pilling for weight loss has been around since the eighties. The biggest reason that using a combination of pills is becoming popular will be the fact that as of right now there are no long term prescription weight loss supplements that have been authorized by the FDA aside from orlistat. The truly disturbing part is the fact that doctors are prescribing these combinations of medications although some people might of the combinations are already rejected or have yet to be authorized by the FDA. Seizures are a side effect with Contrave and mustn't be taken in individuals with seizure disorders. The drug also can raise blood pressure level and heart rate, and really should not be used in people with a history of cardiac event or stroke in the last six months. Blood pressure and pulse should also be measured prior to starting the drug and throughout therapy with all the drug. The FDA also warned that Contrave can raise blood pressure levels and heartbeat and must not be used in patients with uncontrolled high hypertension, in addition to by you are not heart-related and cerebrovascular (circulation dysfunction impacting the mind) disease. Patients with a history of heart attack or stroke in the last six months, life-threatening arrhythmias, or congestive heart failure were excluded in the clinical trials. Those taking Contrave needs to have their heart-rate and pulse monitored regularly. In addition, since the compound includes bupropion, Contrave comes which has a boxed warning to alert medical researchers and patients on the increased likelihood of suicidal thoughts and behaviors connected with antidepressant drugs. The warning also notes that serious neuropsychiatric events have been reported in patients taking bupropion for quitting smoking. Please show your support by clicking the 'Like', 'Subscribe' and 'Share' buttons seen on this page.
